Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718916 | 1.00 | NPY1R (0.50) | NPY1RKMT2AHTTALDH1A1MAPT | |
| SCHEMBL7718948 | 0.82 | NPY1R (0.49) | NPY1RKMT2AHTTALDH1A1MAPT | |
| SCHEMBL7711275 | 0.79 | NPY1R (0.54) | NPY1RKMT2AHTTALDH1A1MAPT | |
| SCHEMBL11507421 | 0.78 | HTT (0.56) | KMT2AHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL7715920 | 0.77 | ADRB1 (0.45) | KMT2AALDH1A1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL7715909 | 0.76 | KCNQ2 (0.48) | NPY1RKMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL7899989 | 0.76 | HTR6 (0.55) | KMT2AHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL5092054 | 0.75 | MAPT (0.55) | KMT2AHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL7711170 | 0.75 | NPC1 (0.55) | KMT2AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL1274938 | 0.75 | HTT (0.73) | KMT2AHTTALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |