Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900009 | 0.84 | HTT (0.49) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL7899993 | 0.77 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL7520363 | 0.73 | GAA (0.63) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL18833848 | 0.73 | LOXL2 (0.53) | MAPTALDH1A1CYP1A2L3MBTL1MAPK1 | |
| SCHEMBL942066 | 0.73 | LOXL2 (0.53) | MAPTALDH1A1CYP1A2L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL11740245 | 0.72 | LOXL2 (0.52) | MAPTALDH1A1CYP1A2L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL1820970 | 0.72 | LOXL2 (0.52) | MAPTALDH1A1CYP1A2L3MBTL1MAPK1 | |
| SCHEMBL15271381 | 0.71 | SIRT6 (0.81) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6151230 | 0.71 | SIRT6 (0.81) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29028271 | 0.68 | POLB (0.69) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194399-B1 | E.G., N1-(2-AMINOETHYL)-4-NITRO-N3-(2-PHENOXYETHYL)-1,3-BENZENEDIAMINE AND N-(4-NITRO-N3-(4-(NITROPHENYL)-1-PIPERA-ZINYL)PHENYL)-1,2-ETHANEDIAMINE; BACTERICIDES; DRUG-RESISTANT -LOW RESISTANCE DEVELOPMENT; LOW HALF LIFE; BROAD SPECTRUM | SCRIPTGEN PHARMACEUTICALS, INC. | 2001-02-27 | — | — | US | claimed |
| US-6194399-B1 | E.G., N1-(2-AMINOETHYL)-4-NITRO-N3-(2-PHENOXYETHYL)-1,3-BENZENEDIAMINE AND N-(4-NITRO-N3-(4-(NITROPHENYL)-1-PIPERA-ZINYL)PHENYL)-1,2-ETHANEDIAMINE; BACTERICIDES; DRUG-RESISTANT -LOW RESISTANCE DEVELOPMENT; LOW HALF LIFE; BROAD SPECTRUM | SCRIPTGEN PHARMACEUTICALS, INC. | 2001-02-27 | — | — | US | disclosed |
| WO-2000021539-A1 | ARYLDIAMINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-04-20 | — | — | WO | disclosed |