Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919629 | 0.93 | MAOA (0.46) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL2961289 | 0.91 | ESR1 (0.43) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL7900276 | 0.89 | ESR1 (0.52) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL4826653 | 0.88 | ESR1 (0.48) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL21435730 | 0.87 | ACHE (0.48) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL29541990 | 0.86 | ESR1 (0.43) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL21332240 | 0.86 | ESR1 (0.43) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL3465721 | 0.85 | ACHE (0.50) | ALDH1A1ESR1MEN1KMT2AACHE | |
| SCHEMBL12415341 | 0.85 | MAOA (0.40) | MAOAKMOALDH1A1GP6ESR1 | |
| SCHEMBL5955974 | 0.85 | MAOA (0.40) | MAOAKMOALDH1A1GP6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6203933-B1 | ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND | TDK CORPORATION (JP) | 2001-03-20 | — | — | US | disclosed |