Sugi Predict

Sugi Predict / Compounds / SCHEMBL12415341

SCHEMBL12415341

SCHEMBL12415341

Ic1c2ccccc2c(-c2cccc(-c3ccccc3)c2)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.40
▸ KMO O15229 1/20 0.39
▸ GP6 Q9HCN6 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ ESR1 P03372 4/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MGLL Q99685 1/20 0.36
▸ ESR2 Q92731 3/20 0.35
▸ ACHE P22303 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ ACMSD Q8TDX5 1/20 0.35
▸ ALOX5 P09917 1/20 0.34
▸ PRSS1 P07477 1/20 0.34
▸ PRSS2 P07478 1/20 0.34
▸ PRSS3 P35030 1/20 0.34
▸ NISCH Q9Y2I1 1/20 0.34
▸ PLA2G2A P14555 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27919629 0.87 MAOA (0.46) MAOAKMOGP6ALDH1A1ESR1
SCHEMBL12415342 0.85 ESR1 (0.43) ALDH1A1ESR1ESR2ACHE
SCHEMBL7900244 0.85 MAOA (0.44) MAOAKMOGP6ALDH1A1ESR1
SCHEMBL295908 0.84 ESR1 (0.46) ALDH1A1ESR1ESR2ACHE
SCHEMBL4826653 0.82 ESR1 (0.48) MAOAKMOGP6ALDH1A1ESR1
SCHEMBL21435730 0.82 ACHE (0.48) MAOAKMOGP6ALDH1A1ESR1
SCHEMBL13016390 0.81 ESR1 (0.36) MAOAKMOESR1MEN1KMT2A
SCHEMBL2961289 0.81 ESR1 (0.43) MAOAKMOGP6ALDH1A1ESR1
SCHEMBL18904909 0.80 CNR1 (0.41) ALDH1A1KMT2AACHE
SCHEMBL5955974 0.79 MAOA (0.40) MAOAKMOGP6ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 — — US disclosed
WO-2021136277-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 — — WO disclosed
US-8283855-B2 Method for synthesis of anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 — — US disclosed
US-8283855-B2 Method for synthesis of anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 — — US disclosed
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-07-14 — — US disclosed
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE CYP1A1, AHR, CYP2C9 MAOA 276/4885KMO 324/4885GP6 3838/4885
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE ODC1, LEF1, PIEZO1 MAOA 191/4885KMO 1283/4885GP6 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.