Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906815 | 0.96 | ESR1 (0.50) | ESR1ESR2MAOAALOX5KMO | |
| SCHEMBL7900244 | 0.89 | MAOA (0.44) | ESR1ESR2MAOAALOX5KMO | |
| SCHEMBL22708077 | 0.88 | HSD17B1 (0.53) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL29330637 | 0.87 | HSD17B1 (0.49) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL7653304 | 0.87 | ALDH1A1 (0.55) | ESR1ESR2MAOAALOX5GP6 | |
| SCHEMBL135027 | 0.87 | ESR1 (0.64) | ESR1ESR2ALOX5ALDH1A1HIF1A | |
| SCHEMBL29406362 | 0.87 | ESR1 (0.64) | ESR1ESR2ALOX5ALDH1A1HIF1A | |
| SCHEMBL5066070 | 0.87 | ESR1 (0.64) | ESR1ESR2ALOX5ALDH1A1HIF1A | |
| SCHEMBL30441010 | 0.87 | ESR1 (0.64) | ESR1ESR2ALOX5ALDH1A1HIF1A | |
| SCHEMBL27919629 | 0.87 | MAOA (0.46) | ESR1ESR2MAOAALOX5KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6203933-B1 | ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND | TDK CORPORATION (JP) | 2001-03-20 | — | — | US | disclosed |