Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900359 | 0.92 | KCNE1 (0.41) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL7910164 | 0.79 | SIRT2 (0.39) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL7900343 | 0.78 | KCNE1 (0.43) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL7906977 | 0.78 | CNR2 (0.41) | ALDH1A1KDM4EGAAHPGDKCNE1 | |
| SCHEMBL7908101 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL7900354 | 0.76 | KCNE1 (0.46) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL6559382 | 0.74 | MAPT (0.45) | ALDH1A1GAASIRT2KCNE1KCNQ1 | |
| SCHEMBL6559918 | 0.70 | TRPV1 (0.38) | ALDH1A1KDM4EGAASIRT2KCNE1 | |
| SCHEMBL8477178 | 0.66 | KCNE1 (0.46) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL6560829 | 0.66 | MAPT (0.41) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |