Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 5/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913688 | 0.91 | CTSD (0.36) | SIRT2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7900359 | 0.86 | KCNE1 (0.41) | SIRT2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL6604070 | 0.79 | ALDH1A1 (0.36) | SIRT2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7910522 | 0.77 | KCNE1 (0.43) | SIRT2ALDH1A1CTSDBACE1KCNA5 | |
| SCHEMBL7910178 | 0.77 | KCNE1 (0.42) | SIRT2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7906977 | 0.74 | CNR2 (0.41) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL7908101 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL6559382 | 0.72 | MAPT (0.45) | SIRT2ALDH1A1GAACTSDBACE1 | |
| SCHEMBL6559918 | 0.71 | TRPV1 (0.38) | SIRT2ALDH1A1GAAKDM4ECTSD | |
| SCHEMBL6558641 | 0.69 | TRPV1 (0.39) | SIRT2CTSDBACE1SIRT1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |