Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893005 | 1.00 | FDPS (0.53) | FDPSMEN1KMT2ATP53MAPT | |
| SCHEMBL7902111 | 0.82 | FDPS (0.56) | FDPSMEN1KMT2ATP53MAPT | |
| SCHEMBL13115720 | 0.81 | RAB9A (0.49) | MEN1KMT2AMAPTHPGDHCAR3 | |
| SCHEMBL1181647 | 0.80 | FDPS (0.56) | FDPSMEN1KMT2ATP53MAPT | |
| SCHEMBL2794101 | 0.79 | HCAR3 (0.46) | HCAR3 | |
| SCHEMBL2789758 | 0.79 | HCAR3 (0.46) | HCAR3 | |
| SCHEMBL7893408 | 0.79 | HCAR3 (0.46) | HCAR3 | |
| SCHEMBL15511709 | 0.79 | CDK9 (0.47) | MEN1KMT2ATP53MAPTHPGD | |
| SCHEMBL15511714 | 0.79 | CDK9 (0.47) | MEN1KMT2ATP53MAPTHPGD | |
| SCHEMBL27310430 | 0.77 | HCAR3 (0.44) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |