Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17362153 | 0.75 | CARM1 (0.41) | PRMT6CARM1KMT2AGBA1SLC6A2 | |
| SCHEMBL16255071 | 0.72 | CHRM2 (0.48) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL31276928 | 0.72 | GBA1 (0.43) | ALDH1A1PRMT6GBA1SLC6A2SLC6A4 | |
| SCHEMBL13906422 | 0.70 | LMNA (0.54) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL11594280 | 0.70 | TAAR1 (0.50) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL11831742 | 0.70 | ALDH1A1 (0.52) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL22542162 | 0.69 | KEAP1 (0.43) | PRMT6CARM1 | |
| SCHEMBL3501486 | 0.69 | CYP3A4 (0.61) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL11009339 | 0.68 | MAOA (0.44) | PRMT6GBA1CCR3 | |
| SCHEMBL11009335 | 0.68 | MAOA (0.44) | PRMT6GBA1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |