Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069680 | 0.83 | MMP8 (0.42) | PIK3CDMMP8MMP1MMP2MMP3 | |
| SCHEMBL22519706 | 0.82 | FOLH1 (0.33) | PIK3CDMAPT | |
| SCHEMBL12308797 | 0.81 | CTSD (0.37) | PIK3CDMMP8LMNA | |
| SCHEMBL24737242 | 0.79 | MCL1 (0.36) | PIK3CDMMP8MCL1MMP1MMP2 | |
| SCHEMBL12308816 | 0.79 | ALDH1A1 (0.36) | PIK3CDMMP8 | |
| SCHEMBL20904149 | 0.78 | PIK3CD (0.32) | PIK3CDMMP8 | |
| SCHEMBL12308834 | 0.76 | SMN1; SMN2 (0.39) | PIK3CDMAPT | |
| SCHEMBL12308836 | 0.76 | PIK3CD (0.39) | PIK3CDMMP8 | |
| SCHEMBL12308383 | 0.76 | ALDH1A1 (0.41) | PIK3CDLMNAMAPT | |
| SCHEMBL12335222 | 0.75 | PIK3CD (0.31) | PIK3CDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063124-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010063123-A1 | LEPTIN AND LEPTIN ANALOG CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2010-06-10 | — | — | WO | disclosed |