Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807074 | 0.83 | FGFR1 (0.57) | FGFR1SRCMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL789680 | 0.81 | FGFR1 (0.55) | FGFR1SRCMEN1KMT2ANPC1 | |
| SCHEMBL8574353 | 0.80 | KMT2A (0.74) | FGFR1SRCMEN1KMT2ANPC1 | |
| SCHEMBL20515329 | 0.80 | PSMB5 (0.71) | MEN1KMT2APSMB5ADORA3ADORA2A | |
| SCHEMBL1786939 | 0.80 | PSMB5 (0.45) | MEN1KMT2ANPC1RAB9ABACE1 | |
| SCHEMBL789883 | 0.76 | MAP4K4 (0.54) | FGFR1SRCMEN1KMT2ANPC1 | |
| SCHEMBL15646572 | 0.76 | HPGD (0.54) | MEN1KMT2ANPC1RAB9ABACE1 | |
| SCHEMBL10277962 | 0.75 | HSD17B1 (0.51) | FGFR1SRCMEN1KMT2ANPC1 | |
| SCHEMBL27632997 | 0.75 | SLC2A1 (0.62) | FGFR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5775666 | 0.74 | BACE1 (0.57) | MEN1KMT2ABACE1PSMB5ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |