Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901264 | 0.97 | KDM4E (0.39) | KDM4EGPR3BCHEACHELMNA | |
| SCHEMBL7893958 | 0.93 | KDM4E (0.41) | KDM4EGPR3ACHELMNAMAPT | |
| SCHEMBL7900647 | 0.78 | KDM4E (0.41) | KDM4EGPR3BCHEACHEMAPT | |
| SCHEMBL16535869 | 0.76 | KDM4E (0.48) | KDM4EGPR3ALDH1A1HPGDPIM1 | |
| SCHEMBL7901266 | 0.74 | KIF11 (0.42) | KDM4EGPR3BCHEACHELMNA | |
| SCHEMBL22049815 | 0.73 | KDM4E (0.45) | KDM4EGPR3ALDH1A1HPGDPIM1 | |
| SCHEMBL11743927 | 0.72 | KIF11 (0.43) | KDM4EGPR3BCHEACHEALDH1A1 | |
| SCHEMBL6919575 | 0.72 | ALDH1A1 (0.49) | KDM4EGPR3LMNAMAPTALDH1A1 | |
| SCHEMBL8088682 | 0.72 | ACHE (0.46) | KDM4EGPR3BCHEACHELMNA | |
| SCHEMBL17409892 | 0.71 | KIF11 (0.42) | KDM4EGPR3BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187783-B1 | ANTITUMOR AGENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-02-13 | — | — | US | disclosed |