Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942070 | 0.91 | CYP19A1 (0.65) | MAOBMAOACYP19A1MAPTMEN1 | |
| SCHEMBL7907924 | 0.88 | CTSV (0.58) | MAOBMAOACYP19A1MAPTMEN1 | |
| SCHEMBL3962253 | 0.88 | MAOB (0.61) | MAOBMEN1KMT2AKDM4ELMNA | |
| SCHEMBL7914592 | 0.86 | MAOB (0.57) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL7907439 | 0.86 | MAOB (0.56) | MAOBKDM4EPOLBALDH1A1 | |
| SCHEMBL7910894 | 0.83 | FFAR4 (0.65) | MAOBMAOAMAPTKMT2ALMNA | |
| SCHEMBL7910948 | 0.83 | MAOB (0.57) | MAOBMAOAMEN1KMT2AKDM4E | |
| SCHEMBL6567396 | 0.83 | MEN1 (0.64) | CYP19A1MAPTMEN1KMT2ACTSV | |
| SCHEMBL7911112 | 0.83 | MAOB (0.57) | MAOBMAOAMEN1KMT2AKDM4E | |
| SCHEMBL6361504 | 0.83 | MEN1 (0.56) | MAOBMAOAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |