Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902108 | 0.86 | RAB9A (0.44) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL12883333 | 0.80 | ALDH1A1 (0.46) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL2792087 | 0.79 | ALOX5AP (0.40) | RAB9AKDM4E | |
| SCHEMBL12932912 | 0.73 | NPC1 (0.49) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL16750002 | 0.72 | ALDH1A1 (0.41) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL12199218 | 0.71 | NPSR1 (0.46) | RAB9AALDH1A1NPC1PKMMEN1 | |
| SCHEMBL15382062 | 0.71 | KIF18A (0.38) | MEN1KMT2AATM | |
| SCHEMBL17841457 | 0.71 | CNR2 (0.51) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL28930806 | 0.70 | NPSR1 (0.45) | SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL21551229 | 0.70 | TSHR (0.48) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |