Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900683 | 0.86 | RAB9A (0.44) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL12883333 | 0.80 | ALDH1A1 (0.46) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL12932912 | 0.73 | NPC1 (0.49) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL16750002 | 0.72 | ALDH1A1 (0.41) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL22032009 | 0.70 | RAB9A (0.47) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL1817853 | 0.69 | GBA1 (0.39) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL182559 | 0.69 | NPC1 (0.53) | RAB9AALDH1A1TSHRNPC1ATM | |
| SCHEMBL30908459 | 0.69 | GBA1 (0.39) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL2033431 | 0.69 | RAB9A (0.55) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL1435912 | 0.69 | NPC1 (0.46) | RAB9AALDH1A1TSHRNPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |