Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602702 | 0.87 | HTT (0.50) | HTTPARP1SGMS2ALDH1A1GAA | |
| SCHEMBL7896335 | 0.83 | NPC1 (0.45) | HTTPARP1ALDH1A1NPC1MAPT | |
| SCHEMBL718082 | 0.82 | PARP1 (0.79) | HTTPARP1SGMS2GAANPC1 | |
| SCHEMBL758009 | 0.82 | HTT (0.59) | HTTPARP1SGMS2ALDH1A1GAA | |
| SCHEMBL1291516 | 0.81 | SGMS2 (0.54) | HTTPARP1SGMS2ALDH1A1GAA | |
| SCHEMBL4724548 | 0.81 | LRRK2 (0.55) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL23541018 | 0.81 | HTT (0.57) | HTTPARP1SGMS2ALDH1A1GAA | |
| SCHEMBL7897895 | 0.80 | LMNA (0.47) | MAPTKMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL25080742 | 0.79 | HTT (0.56) | HTTPARP1SGMS2ALDH1A1GAA | |
| SCHEMBL7896373 | 0.79 | LMNA (0.49) | MAPTKMT2ASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817553-B | The pyrimidinediamine class compound and its derivative and its medical usage of a kind of aromatic radical-heterocyclic substituted | 华东师范大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-104817553-A | Aryl-heterocycle substituted pyrimidinediamine compound and its derivative and pharmaceutical use thereof | UNIV EAST CHINA NORMAL | 2015-08-05 | — | — | CN | disclosed |
| CN-103562379-A | Cell differentiation inducer and differentiation inducing method | UNIV TOKUSHIMA | 2014-02-05 | — | — | CN | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |