Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.54 |
| ▸ | F9 | P00740 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23541018 | 0.98 | HTT (0.57) | HTTPARP1SGMS2F9F10 | |
| Hydrochloric Acid SCHEMBL23541286 | 0.93 | F2 (0.59) | HTTPARP1SGMS2F9F10 | |
| Hydrochloric Acid SCHEMBL5743216 | 0.85 | F2 (0.52) | HTTPARP1SGMS2F9F10 | |
| SCHEMBL30359922 | 0.84 | HTR1A (0.56) | SGMS2F9F10F2ALDH1A1 | |
| SCHEMBL21585887 | 0.84 | HTR1A (0.56) | SGMS2F9F10F2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28500564 | 0.83 | KLK8 (0.55) | SGMS2F9F10F2ALDH1A1 | |
| SCHEMBL718082 | 0.82 | PARP1 (0.79) | HTTPARP1SGMS2NPC1MAPT | |
| SCHEMBL7900714 | 0.82 | HTT (0.59) | HTTPARP1SGMS2LTA4HMAPK14 | |
| SCHEMBL4143074 | 0.82 | NPC1 (0.55) | HTTPARP1SGMS2F9F10 | |
| SCHEMBL6952466 | 0.81 | NPC1 (0.55) | HTTPARP1SGMS2LTA4HMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020201305-A1 | 4-(2,4-BIS(2-HYDROXYPHENYL)-1H-IMIDAZOL-1-YL)BENZOIC ACID DERIVATIVES AS NOVEL IRON CHELATORS | VIFOR (INTERNATIONAL) AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020201305-A1 | 4-(2,4-BIS(2-HYDROXYPHENYL)-1H-IMIDAZOL-1-YL)BENZOIC ACID DERIVATIVES AS NOVEL IRON CHELATORS | VIFOR (INTERNATIONAL) AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| EP-1928818-B1 | PESTICIDE BENZYLOXY- AND PHENETYL-SUBSTITUTED PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1928818-A1 | PESTICIDE BENZYLOXY- AND PHENETYL-SUBSTITUTED PHENYL-AMIDINE DERIVATIVES | Bayer CropScience AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007031526-A1 | PESTICIDE BENZYLOXY- AND PHENETYL-SUBSTITUTED PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1237897-A2 | ANTITHROMBOTIC COMPOUND | Akzo Nobel N.V. (NL) | 2002-09-11 | — | — | EP | disclosed |
| CN-1340049-A | 4- (heterocyclylsulfonylamino) -5-methoxy-6- (2-methoxyphenoxy) -2-phenyl-or-pyridylpyrimidines as endothelin receptor antagonists | HOFFMANN LA ROCHE (CH) | 2002-03-13 | — | — | CN | disclosed |
| WO-2001042262-A2 | ANTITHROMBOTIC COMPOUND | AKZO NOBEL N.V. (NL) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | HTT 3362/4885PARP1 3786/4885SGMS2 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.