SCHEMBL7900910

SCHEMBL7900910

CC(C)(C)CC(C)(C)c1cc(-n2nc3ccccc3n2)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.39
KDM4E B2RXH2 5/20 0.39
HPGD P15428 3/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
NR3C1 P04150 5/20 0.35
ALDH1A1 P00352 6/20 0.33
NR1I2 O75469 1/20 0.33
CYP2C9 P11712 1/20 0.33
MIF P14174 1/20 0.33
TYR P14679 1/20 0.33
ALOX15 P16050 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27622566 0.87 NPC1 (0.35) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL10630720 0.87 NPC1 (0.43) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL5814259 0.84 ALDH1A1 (0.50) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL28884858 0.80 NPC1 (0.41) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL3320508 0.79 RAB9A (0.37) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL27622570 0.79 MAPT (0.35) NPC1RAB9AKDM4EHPGDALDH1A1
SCHEMBL28595117 0.78 PTPN5 (0.34) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL6567729 0.77 PPARG (0.36) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL27622571 0.77 KCNMA1 (0.32) KDM4E
SCHEMBL4398146 0.76 KDM4E (0.36) NPC1RAB9ALMNAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655323-B2 Poly(amide-imide) copolymer film and method for preparing same LG CHEM, LTD. (KR) 2023-05-23 US disclosed
US-20200369816-A1 POLY(AMIDE-IMIDE) COPOLYMER FILM AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2020-11-26 US disclosed
CN-1220911-C Cellulose ester film and its producing method FUJI PHOTO FILM CO LTD (JP) 2005-09-28 CN disclosed
CN-1352408-A Cellulose ester film and its producing method FUJI PHOTO FILM CO LTD (JP) 2002-06-05 CN disclosed
US-6194494-B1 STABILIZERS FOR POLYVINYL CHLORIDE AGAINST OXIDATION WITCO VINYL ADDITIVES GMBH (DE) 2001-02-27 US disclosed
CN-1025040-C UV-light-stabilized polyoxymethylene molding compositions HOECHST CELANESE CORP (US) 1994-06-15 CN disclosed