Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.66 |
| ▸ | PI4KA | P42356 | 10/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.58 |
| ▸ | MTOR | P42345 | 3/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807092 | 0.93 | PI4KA (0.55) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL790763 | 0.92 | PIK3CG (0.62) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL790869 | 0.88 | PI4KA (0.62) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL790186 | 0.88 | PI4KA (0.53) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL791172 | 0.84 | PI4KA (0.68) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL10277973 | 0.84 | PI4KA (0.49) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL789337 | 0.84 | PIK3CG (0.77) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL790388 | 0.83 | PIK3CG (0.56) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL790832 | 0.81 | PIK3CG (0.51) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL790131 | 0.81 | PIK3CD (0.56) | PIK3CGPI4KAPIK3CDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |