Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.62 |
| ▸ | PI4KA | P42356 | 8/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.59 |
| ▸ | MTOR | P42345 | 5/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790102 | 0.92 | PIK3CG (0.66) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807092 | 0.88 | PI4KA (0.55) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807155 | 0.88 | PIK3CG (0.62) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL789833 | 0.87 | PIK3CG (0.61) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| Lithium SCHEMBL789835 | 0.87 | PIK3CG (0.61) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| Lithium Ion SCHEMBL789834 | 0.86 | PI4KA (0.58) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790186 | 0.86 | PI4KA (0.53) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790028 | 0.85 | PI4KA (0.60) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790388 | 0.84 | PIK3CG (0.56) | PIK3CGPI4KAPIK3CAMTORSLC40A1 | |
| SCHEMBL790869 | 0.84 | PI4KA (0.62) | PIK3CGPI4KAPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |