Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 6/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | SI | P14410 | 6/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426720 | 0.88 | GAA (0.59) | KMT2ASMN1; SMN2ALDH1A1MEN1MGAM | |
| SCHEMBL7196792 | 0.87 | RPS6KA3 (0.54) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL424346 | 0.86 | F12 (0.63) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL425448 | 0.86 | GAA (0.54) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL425567 | 0.85 | F12 (0.66) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11294103 | 0.83 | KCNMA1 (0.57) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL425439 | 0.82 | MGLL (0.53) | KMT2ASMN1; SMN2ALDH1A1MEN1MGAM | |
| SCHEMBL12593860 | 0.80 | ASAH1 (0.62) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17875212 | 0.79 | ASAH1 (0.59) | KMT2AALDH1A1MGAMAMY1AGAA | |
| SCHEMBL16706437 | 0.78 | MGAM (0.77) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |