Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | MGAM | O43451 | 6/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.50 |
| ▸ | SI | P14410 | 6/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426720 | 0.88 | GAA (0.59) | F12KMT2AFAAHMGLLMEN1 | |
| SCHEMBL7196792 | 0.87 | RPS6KA3 (0.54) | F12KMT2AMGLLMEN1ALDH1A1 | |
| SCHEMBL7901101 | 0.86 | RAB9A (0.62) | F12KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL425448 | 0.86 | GAA (0.54) | F12KMT2AFAAHMGLLMEN1 | |
| SCHEMBL425439 | 0.82 | MGLL (0.53) | F12KMT2AFAAHMGLLMEN1 | |
| SCHEMBL425567 | 0.82 | F12 (0.66) | F12KMT2AFAAHMGLLMEN1 | |
| SCHEMBL12648516 | 0.80 | F12 (0.59) | F12GLATHRBKMT2AFAAH | |
| SCHEMBL29479884 | 0.78 | F12 (1.00) | F12GLATHRBKMT2AALDH1A1 | |
| SCHEMBL2494940 | 0.78 | F12 (1.00) | F12GLATHRBKMT2AALDH1A1 | |
| SCHEMBL13182368 | 0.77 | RAB9A (0.77) | THRBKMT2AMGLLMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | F12 785/4885GLA 901/4885THRB 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.