Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789519 | 0.87 | CNR2 (0.36) | CNR2HRH2HRH1 | |
| SCHEMBL7898298 | 0.86 | WNT3A (0.32) | CNR2ATMKLK5PADI4HRH2 | |
| SCHEMBL7901623 | 0.84 | ALOX5AP (0.33) | ATMKLK5HRH2HRH1CCNK | |
| SCHEMBL7898758 | 0.83 | CNR2 (0.36) | CNR2KLK5PADI4HRH2HRH1 | |
| SCHEMBL7891178 | 0.83 | CNR2 (0.36) | CNR2KLK5PADI4HRH2HRH1 | |
| SCHEMBL7896622 | 0.83 | CNR2 (0.35) | CNR2KLK5PADI4HRH2HRH1 | |
| SCHEMBL7901244 | 0.82 | HTR6 (0.34) | CNR2KLK5HRH2HRH1PTPN1 | |
| SCHEMBL2790219 | 0.81 | PADI4 (0.41) | CNR2KLK5PADI4HRH2HRH1 | |
| SCHEMBL2791310 | 0.81 | CNR2 (0.36) | CNR2 | |
| SCHEMBL7898510 | 0.81 | ATM (0.33) | ATMKLK5PADI4HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |