Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592104 | 0.94 | NPSR1 (0.55) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL7676239 | 0.90 | NPSR1 (0.56) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL22809569 | 0.82 | PKM (0.52) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL22809528 | 0.80 | PKM (0.57) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL14234223 | 0.77 | PKM (0.51) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL6970766 | 0.75 | ALDH1A1 (0.49) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL6970770 | 0.75 | PKM (0.50) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL14234225 | 0.73 | PKM (0.53) | NPSR1PKMKMT2AMEN1L3MBTL1 | |
| SCHEMBL3926414 | 0.73 | TDP1 (0.52) | NPSR1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL7821174 | 0.72 | PKM (0.65) | NPSR1PKMKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191280-B1 | REACTING SUBSTITUTED 2-HALOPYRIDINE DERIVATIVE WITH A THIO COMPOUND IN PRESENCE OF COPPER CATALYST TO GIVE A PYRIDINE THIOETHER, AND THEN OXIDIZING THE THIOETHER INTERMEDIATE TO FORM SULFOXIDE OR SULFONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0984935-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054139-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-03 | — | — | WO | disclosed |