Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905475 | 0.89 | MEN1 (0.40) | MAPK1NOTUMMRGPRX4ALDH1A1KDM4E | |
| SCHEMBL8129422 | 0.85 | NOTUM (0.39) | CYP4F2CYP4A11MAPK1NOTUMBAZ2B | |
| SCHEMBL7901344 | 0.84 | BAZ2B (0.39) | BAZ2BBAZ2AMRGPRX4ALDH1A1KDM4E | |
| SCHEMBL6699195 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11MAPK1NOTUMBAZ2B | |
| SCHEMBL8137674 | 0.75 | TP53 (0.43) | CYP4F2CYP4A11MAPK1NOTUMBAZ2B | |
| SCHEMBL8392488 | 0.74 | KDM4E (0.34) | ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL7901403 | 0.74 | MCL1 (0.41) | — | |
| SCHEMBL8138015 | 0.73 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPK1BAZ2BBAZ2A | |
| SCHEMBL7901519 | 0.73 | GAA (0.33) | NOTUMMRGPRX4ALDH1A1KDM4EHPGD | |
| SCHEMBL7901494 | 0.73 | PPOX (0.50) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | claimed |
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0902029-A1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |