SCHEMBL7901344

SCHEMBL7901344

CCOC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n3ccnc23)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.39
BAZ2A Q9UIF9 1/20 0.39
KDM4E B2RXH2 4/20 0.34
HPGD P15428 3/20 0.34
ALDH1A1 P00352 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
JMJD6 Q6NYC1 1/20 0.34
GUSB P08236 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
GAA P10253 3/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7901519 0.90 GAA (0.33) KDM4EHPGDALDH1A1GUSBMRGPRX4
SCHEMBL7901494 0.85 PPOX (0.50) KDM4EHPGDALDH1A1GAAGLA
SCHEMBL7901370 0.84 CYP4F2 (0.39) BAZ2BBAZ2AKDM4EHPGDALDH1A1
SCHEMBL7901376 0.83 PPOX (0.50) PPOX
SCHEMBL7901378 0.83 L3MBTL1 (0.41) KDM4EHPGDALDH1A1GAACASP1
SCHEMBL7905653 0.83 ALDH1A1 (0.36) KDM4EHPGDALDH1A1TSHRHSD17B10
SCHEMBL7901544 0.83 PPOX (0.33) PPOX
SCHEMBL7894121 0.83 PPOX (0.35) KDM4EHPGDALDH1A1HSD17B10PPOX
SCHEMBL6336900 0.81 BAZ2B (0.46) BAZ2BBAZ2AKDM4EHPGDALDH1A1
SCHEMBL8137614 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US claimed
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US disclosed
EP-0902029-A1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-17 EP disclosed