Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901513 | 0.83 | PPOX (0.36) | MCL1PPOX | |
| SCHEMBL8464400 | 0.80 | PTGS2 (0.35) | MCL1PTGS2FPR2DRD2DRD3 | |
| SCHEMBL8466103 | 0.79 | MCL1 (0.36) | MCL1PTGS2FPR2PPOX | |
| SCHEMBL7905475 | 0.78 | MEN1 (0.40) | — | |
| SCHEMBL8137605 | 0.75 | — | — | |
| SCHEMBL8122021 | 0.74 | MCL1 (0.34) | MCL1 | |
| SCHEMBL7901370 | 0.74 | CYP4F2 (0.39) | — | |
| SCHEMBL8138124 | 0.73 | BCAT2 (0.33) | — | |
| SCHEMBL7901426 | 0.72 | MCL1 (0.32) | MCL1 | |
| SCHEMBL8461149 | 0.70 | AR (0.33) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | claimed |
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0902029-A1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |