SCHEMBL7901382

SCHEMBL7901382

COC(=O)C(C)Sc1cc(-n2c(=O)cc(C(F)(F)F)n3ccnc23)c(F)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
MALT1 Q9UDY8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894121 0.92 PPOX (0.35) MAPK1
SCHEMBL7894127 0.83 MAPK1 (0.31) MAPK1MALT1
SCHEMBL7899859 0.83 PPOX (0.40) MAPK1MALT1
SCHEMBL7901260 0.83 KMT2A (0.35)
SCHEMBL7901519 0.81 GAA (0.33) MALT1
SCHEMBL7905653 0.80 ALDH1A1 (0.36) MAPK1
SCHEMBL7894085 0.78 PPOX (0.40)
SCHEMBL7901544 0.78 PPOX (0.33)
SCHEMBL7894182 0.78 LMNA (0.41) MAPK1
SCHEMBL7901404 0.78 PPOX (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US claimed
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US disclosed
EP-0902029-A1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-17 EP disclosed