Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901260 | 0.91 | KMT2A (0.35) | CYP1A2CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL7894121 | 0.86 | PPOX (0.35) | ALDH1A1HSD17B10ALOX15LMNAPOLB | |
| SCHEMBL7901494 | 0.84 | PPOX (0.50) | ALDH1A1HSD17B10TSHRLMNAPPOX | |
| SCHEMBL7901344 | 0.83 | BAZ2B (0.39) | ALDH1A1CYP1A2CYP2C19HSD17B10TSHR | |
| SCHEMBL7901378 | 0.83 | L3MBTL1 (0.41) | ALDH1A1HSD17B10ALOX15POLBPPOX | |
| SCHEMBL7901382 | 0.80 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL7901376 | 0.80 | PPOX (0.50) | PPOX | |
| SCHEMBL7901544 | 0.79 | PPOX (0.33) | PPOX | |
| SCHEMBL7894182 | 0.77 | LMNA (0.41) | ALDH1A1TSHRLMNAPOLBPPOX | |
| SCHEMBL7901519 | 0.77 | GAA (0.33) | ALDH1A1HSD17B10TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | claimed |
| US-6191070-B1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0902029-A1 | Pyrimidinone derivatives and herbicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |