SCHEMBL7901558

SCHEMBL7901558

O=C(O)CC[C@H](NC(=O)C1CCCCC1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.55
NAALAD2 Q9Y3Q0 3/20 0.55
RIMKLA Q8IXN7 1/20 0.55
EPHX2 P34913 1/20 0.51
POLB P06746 1/20 0.49
PKLR P30613 1/20 0.44
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322256 0.87 KMT2A (0.43) FOLH1NAALAD2RIMKLAEPHX2POLB
SCHEMBL5322259 0.87 KMT2A (0.43) FOLH1NAALAD2RIMKLAEPHX2POLB
SCHEMBL9829322 0.83 NAAA (0.45) LMNA
SCHEMBL9829324 0.83 NAAA (0.45) LMNA
SCHEMBL23967395 0.83 MME (0.46) PKLRLMNA
SCHEMBL7898517 0.83 MME (0.46) PKLRLMNA
SCHEMBL10669991 0.81 LMNA (0.43) LMNA
SCHEMBL28910144 0.81 MME (0.45) PKLRLMNA
SCHEMBL10669986 0.81 LMNA (0.43) LMNA
SCHEMBL24690525 0.81 FOLH1 (0.62) FOLH1NAALAD2RIMKLAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6180140-B1 SUITABLE FOR ORAL ADMINISTRATION OF BIOLOGICALLY ACTIVE AGENTS TO ANIMALS EMISPHERE TECHNOLOGIES, INC. 2001-01-30 US disclosed
US-5935601-A Modified amino acids for drug delivery EMISPHERE TECHNOLOGIES, INC. (US) 1999-08-10 US disclosed
EP-0812212-A4 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECH INC (US) 1999-04-14 EP disclosed
EP-0758843-A4 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECH INC (US) 1998-05-20 EP disclosed
US-5709861-A PEPTIDES WITH ANTIGENS AND PROCESS FOR MIXING EMISPHERE TECHNOLOGIES, INC. (US) 1998-01-20 US disclosed
EP-0812212-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS Emisphere Technologies, Inc. (US) 1997-12-17 EP disclosed
US-5629020-A Modified amino acids for drug delivery EMISPHERE TECHNOLOGIES, INC. (US) 1997-05-13 US disclosed
EP-0758843-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY Emisphere Technologies, Inc. (US) 1997-02-26 EP disclosed
WO-1996021464-A9 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS 1996-11-14 WO disclosed
WO-1996021464-A1 COMPOSITIONS FOR THE DELIVERY OF ANTIGENS EMISPHERE TECHNOLOGIES, INC. (US) 1996-07-18 WO disclosed
WO-1995028838-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECHNOLOGIES, INC. (US) 1995-11-02 WO disclosed