Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669991 | 1.00 | LMNA (0.43) | LMNATDP1NAAAMEN1KMT2A | |
| SCHEMBL9829324 | 0.98 | NAAA (0.45) | LMNATDP1NAAAMEN1KMT2A | |
| SCHEMBL9829322 | 0.98 | NAAA (0.45) | LMNATDP1NAAAMEN1KMT2A | |
| SCHEMBL23441778 | 0.97 | RECQL (0.44) | LMNATDP1NAAAMEN1KMT2A | |
| SCHEMBL1950775 | 0.93 | TDP1 (0.48) | LMNATDP1MEN1KMT2ATP53 | |
| SCHEMBL1950778 | 0.93 | TDP1 (0.48) | LMNATDP1MEN1KMT2ATP53 | |
| SCHEMBL9829901 | 0.89 | NAAA (0.50) | LMNANAAASMN1; SMN2PADI1PADI4 | |
| SCHEMBL9829904 | 0.89 | NAAA (0.50) | LMNANAAASMN1; SMN2PADI1PADI4 | |
| SCHEMBL10482744 | 0.87 | NOD1 (0.45) | LMNATDP1NAAAMEN1KMT2A | |
| SCHEMBL11392973 | 0.87 | LMNA (0.41) | LMNANAAASMN1; SMN2PADI1PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |