Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829322 | 1.00 | NAAA (0.45) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL10669991 | 0.98 | LMNA (0.43) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL10669986 | 0.98 | LMNA (0.43) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL23441778 | 0.95 | RECQL (0.44) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL1950775 | 0.91 | TDP1 (0.48) | LMNATDP1MEN1KMT2A | |
| SCHEMBL1950778 | 0.91 | TDP1 (0.48) | LMNATDP1MEN1KMT2A | |
| SCHEMBL9829901 | 0.90 | NAAA (0.50) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL9829904 | 0.90 | NAAA (0.50) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL17026719 | 0.88 | NAAA (0.55) | NAAASMN1; SMN2 | |
| SCHEMBL6502285 | 0.86 | PADI1 (0.45) | NAAASMN1; SMN2PADI1PADI4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |