SCHEMBL7901727

SCHEMBL7901727

O=S(=O)(Cl)Cl.O=S(=O)(F)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
ALDH1A1 P00352 1/20 0.59
HSD17B10 Q99714 1/20 0.59
HTR6 P50406 1/20 0.50
APOBEC3G Q9HC16 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
TSHR P16473 2/20 0.46
CA12 O43570 2/20 0.46
CA7 P43166 2/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19110981 0.92 HTR6 (0.58) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
SCHEMBL323729 0.92 HTR6 (0.58) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
Hydrochloric Acid SCHEMBL30184245 0.89 HTR6 (0.55) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
Hydrochloric Acid SCHEMBL930597 0.89 HTR6 (0.55) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
Phosphoric Acid SCHEMBL28712122 0.85 ALDH1A1 (0.48) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
Bicarbonate SCHEMBL29219000 0.84 TSHR (0.52) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
SCHEMBL8014338 0.82 CA2 (0.48) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
SCHEMBL10999079 0.79 TDP1 (0.84) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
Ethylamine SCHEMBL1436591 0.78 PSIP1 (0.54) TDP1ALDH1A1HSD17B10HTR6APOBEC3G
(Phenylsulfonyl)Benzene SCHEMBL27510910 0.78 HTR6 (0.82) TDP1ALDH1A1HSD17B10HTR6CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476515-A Removing natural lens from capsular sac, injecting modified collagen composition to fill sac, exposing to polymerization agent to polymerize and form intraocular lens AUTOGENESIS TECHNOLOGIES, INC. (US) 1995-12-19 US claimed
WO-1993002639-A1 INJECTABLE COLLAGEN-BASED COMPOSITIONS FOR MAKING INTRAOCULAR LENS AUTOGENESIS TECHNOLOGIES, INC. (US) 1993-02-18 WO claimed
EP-4337258-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2024-03-20 EP disclosed
US-20220362438-A1 Derivatized or Rapidly Polymerizing Collagen Compositions for Tissue Augmentation Containing Nonresorbable or Slowly Resorbable Polymers SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2022-11-17 US disclosed
WO-2022237900-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2022-11-17 WO disclosed
US-6204365-B1 Collagen modulators for use in photoablation eximer laser keratectomy COLLAGENESIS, INC. 2001-03-20 US disclosed
US-5861486-A Collagen modulators for use in photoablation eximer laser keratectomy EUCLID SYSTEMS CORPORATION 1999-01-19 US disclosed
US-5492135-A Collagen modulators for use in photoablation excimer laser keratectomy COLLAGEN MATRIX TECHNOLOGIES, INC. 1996-02-20 US disclosed
US-5476515-A Removing natural lens from capsular sac, injecting modified collagen composition to fill sac, exposing to polymerization agent to polymerize and form intraocular lens AUTOGENESIS TECHNOLOGIES, INC. (US) 1995-12-19 US disclosed
WO-1994005216-A1 COLLAGEN MODULATORS FOR USE IN PHOTOABLATION EXIMER LASER KERATECTOMY AUTOGENESIS TECHNOLOGIES, INC. (US) 1994-03-17 WO disclosed
WO-1993002639-A1 INJECTABLE COLLAGEN-BASED COMPOSITIONS FOR MAKING INTRAOCULAR LENS AUTOGENESIS TECHNOLOGIES, INC. (US) 1993-02-18 WO disclosed