Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903508 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL10521222 | 0.86 | KMT2A (0.48) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL9407113 | 0.86 | KMT2A (0.48) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL6511218 | 0.84 | ZDHHC2 (0.38) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL9647538 | 0.83 | KMT2A (0.43) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL5705981 | 0.82 | KMT2A (0.47) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL6514850 | 0.80 | KMT2A (0.36) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL8934451 | 0.78 | KMT2A (0.48) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL9487568 | 0.78 | THRB (0.44) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL5705986 | 0.77 | KMT2A (0.47) | ALDH1A1LMNAKMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6238541-B1 | ADHESION; CORROSION RESISTANCE; SURFACE TREATMENT | NIPPON PAINT CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |