Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514850 | 0.86 | KMT2A (0.36) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL1679233 | 0.85 | ZDHHC2 (0.40) | ZDHHC2ZDHHC20TGM2EPHX2MGLL | |
| SCHEMBL7901795 | 0.84 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL9407113 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL10521222 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL9647538 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL9487568 | 0.76 | THRB (0.44) | TGM2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7903508 | 0.71 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL31447344 | 0.71 | KMT2A (0.57) | KMT2AALDH1A1LMNAMAPTHTT | |
| Trifluoromethanesulfonic Acid SCHEMBL31564973 | 0.70 | KMT2A (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050151286-A1 | Gradient refrective-index plastic rod and method for making the same | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2005-07-14 | — | — | US | disclosed |