Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 9/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235602 | 0.96 | NR1I2 (0.43) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL29086820 | 0.87 | NR1I2 (0.39) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL29242328 | 0.87 | ESR1 (0.50) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL18692001 | 0.87 | NR1I2 (0.39) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL11979357 | 0.87 | NR1H2 (0.46) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL27985572 | 0.84 | NR1I2 (0.38) | NR1I2ESR1ESR2HPGDRORA | |
| SCHEMBL18691997 | 0.84 | ESR1 (0.54) | NR1I2ESR1ESR2HPGDNR1H2 | |
| SCHEMBL3482615 | 0.84 | ACHE (0.47) | NR1I2HPGD | |
| SCHEMBL2921010 | 0.82 | LMNA (0.44) | NR1I2 | |
| SCHEMBL29086707 | 0.82 | NR1I2 (0.37) | NR1I2ESR1ESR2HPGDRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184269-B1 | FLAME RETARDANT MATERIAL | GENERAL MOTORS CORPORATION | 2001-02-06 | — | — | US | disclosed |