Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235602 | 0.87 | NR1I2 (0.43) | ESR1ESR2HPGDNR1I2NR1H2 | |
| SCHEMBL2144488 | 0.85 | ESR1 (0.56) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL7902561 | 0.84 | NR1I2 (0.42) | ESR1ESR2HPGDNR1I2NR1H2 | |
| SCHEMBL29086820 | 0.79 | NR1I2 (0.39) | ESR1ESR2HPGDNR1I2NR1H2 | |
| SCHEMBL78718 | 0.79 | ESR1 (0.56) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL29242328 | 0.79 | ESR1 (0.50) | ESR1ESR2HPGDNR1I2NR1H2 | |
| SCHEMBL11979357 | 0.79 | NR1H2 (0.46) | ESR1ESR2HPGDACHENR1I2 | |
| SCHEMBL834965 | 0.79 | ESR1 (0.80) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL18692001 | 0.79 | NR1I2 (0.39) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL3482615 | 0.77 | ACHE (0.47) | LMNAHPGDALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723845-B2 | Process for preparing linear carbosiloxane polymers | DOW SILICONES CORPORATION (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200079911-A1 | PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS | DOW CORNING EUROPE S.A. | 2020-03-12 | — | — | US | disclosed |
| EP-3153540-B1 | PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS | DOW CORNING (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017062091-A1 | PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS | DOW CORNING CORPORATION (US) | 2017-04-13 | — | — | WO | disclosed |
| EP-3153540-A1 | PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS | Dow Corning Corporation (US) | 2017-04-12 | — | — | EP | disclosed |