Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | UNG | P13051 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664238 | 0.95 | ALDH1A1 (0.55) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| Benzaldehyde SCHEMBL1389484 | 0.90 | ALDH1A1 (0.70) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL5446914 | 0.90 | ALDH1A1 (0.60) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL16381738 | 0.88 | ALDH1A1 (0.59) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL28460866 | 0.86 | TRIM24 (0.67) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL31503979 | 0.85 | TRIM24 (0.50) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL16050814 | 0.85 | MAOA (0.48) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL18001570 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL16406661 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL14426269 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TRIM24TRIM33CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220416172-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-12-29 | — | — | US | disclosed |
| US-10544360-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| CN-105377863-B | polycyclic compounds | 默克专利有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-10205106-B2 | Polycyclic compounds | MERCK PATENT GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-10205106-B2 | Polycyclic compounds | MERCK PATENT GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| EP-2787053-B1 | Polymeric materials | MERCK PATENT GMBH (DE) | 2018-11-21 | — | — | EP | disclosed |
| EP-3016959-B1 | POLYCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-3016959-B1 | POLYCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20160204358-A1 | POLYCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012048900-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. . (DE) | 2012-04-19 | — | — | WO | disclosed |
| CN-1099407-C | Novel amino acid derivatives with improved multi-drug resistance activity | VERTEX PAHRMACEUTICAL INC (US) | 2003-01-22 | — | — | CN | disclosed |
| US-6274556-B1 | ADMINISTERING POLYPEPTIDE DERIVATIVE TO TREAT INFLAMMATORY BOWEL DISEASE AND TO PREVENT LEUKOCYTE INFILTRATION INTO TISSUES | MILLENNIUM PHARMACEUTICALS, INC. | 2001-08-14 | — | — | US | disclosed |
| US-5942532-A | INHIBITORS OF HISTIDINE PROTEIN KINASE; BACTERIA RESISTANT TO OTHER ANTIBIOTICS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1999011627-A1 | 2-SUBSTITUTED PHENYL-BENZIMIDAZOLE ANTIBACTERIAL AGENTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| EP-0871670-A2 | INHIBITORS OF MAdCAM-1-MEDIATED INTERACTIONS AND METHODS OF USE THEREFOR | Leukosite, Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025351-A2 | INHIBITORS OF MAdCAM-1-MEDIATED INTERACTIONS AND METHODS OF USE THEREFOR | LEUKOSITE, INC. (US) | 1997-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220416172-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | NDUFS5, KCNJ2, EHMT2 | ALDH1A1 524/4885CYP2A6 3913/4885TRIM24 3545/4885 |
| US-20160204358-A1 | POLYCYCLIC COMPOUNDS | VDAC2, VDAC3, KCNC1 | ALDH1A1 2257/4885CYP2A6 3735/4885TRIM24 3126/4885 |
| US-10205106-B2 | Polycyclic compounds | VDAC2, VDAC3, KCNC1 | ALDH1A1 2257/4885CYP2A6 3735/4885TRIM24 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.