Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28524523 | 0.89 | LMNA (0.43) | TSHRTP53ALDH1A1LMNARECQL | |
| Benzoic Acid SCHEMBL10579966 | 0.88 | TSHR (0.42) | TSHRTP53ALDH1A1LMNARECQL | |
| Hydrogen Peroxide SCHEMBL27497974 | 0.87 | RECQL (0.54) | TSHRRECQL | |
| Aniline SCHEMBL8927846 | 0.87 | ALDH1A1 (0.48) | TSHRTP53ALDH1A1LMNARECQL | |
| SCHEMBL8065973 | 0.86 | RECQL (0.55) | TSHRRECQL | |
| SCHEMBL283123 | 0.86 | RECQL (0.55) | TSHRRECQL | |
| SCHEMBL5075105 | 0.86 | RECQL (0.55) | TSHRRECQL | |
| SCHEMBL2119563 | 0.86 | RECQL (0.55) | TSHRRECQL | |
| SCHEMBL11044262 | 0.86 | RECQL (0.55) | TSHRRECQL | |
| SCHEMBL544411 | 0.86 | RECQL (0.55) | TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9888689-B2 | Compositions containing a pyripyropene insecticide and an adjuvant | BASF SE (DE) | 2018-02-13 | — | — | US | disclosed |
| EP-2615919-B1 | COMPOSITION CONTAINING A PYRIPYROPENE INSECTICIDE AND AN ADJUVANT | BASF SE (DE) | 2015-01-14 | — | — | EP | disclosed |
| US-20130190360-A1 | Compositions Containing a Pyripyropene Insecticide and an Adjuvant | BASF SE (DE) | 2013-07-25 | — | — | US | disclosed |
| EP-2615919-A2 | COMPOSITION CONTAINING A PYRIPYROPENE INSECTICIDE AND AN ADJUVANT | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035015-A2 | COMPOSITION CONTAINING A PYRIPYROPENE INSECTICIDE AND AN ADJUVANT | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| US-20100087542-A1 | IMPROVEMENT OF THE BIOLOGICAL ACTION OF AGROCHEMICAL COMPOSITIONS WHEN APPLIED TO THE CULTIVATION SUBSTRATE, SUITABLE FORMULATIONS AND USE THEREOF | BAYER CROPSCIENCE AKTIENGESELLSHAFT (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20090306147-A1 | BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087542-A1 | IMPROVEMENT OF THE BIOLOGICAL ACTION OF AGROCHEMICAL COMPOSITIONS WHEN APPLIED TO THE CULTIVATION SUBSTRATE, SUITABLE FORMULATIONS AND USE THEREOF | DDT, GAP43, DDC | TSHR 4162/4885TP53 1746/4885PLA2G4B 51/4885 |
| US-20090306147-A1 | BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF | CYP51A1, CYP21A2, CYP4X1 | TSHR 2653/4885TP53 3867/4885PLA2G4B 677/4885 |
| US-20130190360-A1 | Compositions Containing a Pyripyropene Insecticide and an Adjuvant | DDT, PIR, ACHE | TSHR 1038/4885TP53 68/4885PLA2G4B 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.