Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900415 | 0.81 | USP30 (0.40) | USP30ACKR3HTR6BCHEALOX5AP | |
| SCHEMBL7898714 | 0.80 | MMP1 (0.38) | USP30ALOX5APFEN1ALDH1A1GPR119 | |
| SCHEMBL7898814 | 0.78 | HTR6 (0.39) | USP30ACKR3HTR6BCHEALOX5AP | |
| SCHEMBL7894370 | 0.76 | SCN9A (0.39) | USP30ALOX5APFEN1ALDH1A1GPR119 | |
| SCHEMBL7896607 | 0.76 | HTR6 (0.41) | USP30ACKR3HTR6BCHEALDH1A1 | |
| SCHEMBL7900912 | 0.76 | TRPV3 (0.40) | USP30ACKR3JAK2JAK1ALOX5AP | |
| SCHEMBL7893412 | 0.74 | ALOX5AP (0.39) | USP30ACKR3JAK2JAK1ALOX5AP | |
| SCHEMBL7902460 | 0.74 | MEN1 (0.40) | USP30ACKR3JAK2JAK1ALOX5AP | |
| SCHEMBL7899044 | 0.73 | TRPV3 (0.38) | USP30ALOX5APFEN1GPR119 | |
| SCHEMBL7896805 | 0.73 | HTR6 (0.46) | USP30ACKR3HTR6BCHEALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |