Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT7 | O95251 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899044 | 0.93 | TRPV3 (0.38) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7900415 | 0.88 | USP30 (0.40) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7894370 | 0.85 | SCN9A (0.39) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7902460 | 0.82 | MEN1 (0.40) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7893412 | 0.79 | ALOX5AP (0.39) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7898714 | 0.79 | MMP1 (0.38) | ALOX5APFEN1SCN9AUSP30GPR119 | |
| SCHEMBL7899660 | 0.78 | USP30 (0.41) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7898814 | 0.76 | HTR6 (0.39) | TRPV3ALOX5APFEN1SCN9AUSP30 | |
| SCHEMBL7903239 | 0.76 | USP30 (0.39) | ALOX5APFEN1USP30GPR119HDAC4 | |
| SCHEMBL7897488 | 0.72 | USP30 (0.42) | SCN9AUSP30MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |