SCHEMBL790348

SCHEMBL790348

COC(=O)[C@H](C)NP(=S)(Cl)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 9/20 0.50
MAPK1 P28482 1/20 0.45
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM1A O60341 1/20 0.40
RECQL P46063 1/20 0.40
ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17198445 0.88 BTN3A1 (0.52) BTN3A1ELANE
SCHEMBL784413 0.88 BTN3A1 (0.52) BTN3A1ELANE
SCHEMBL15052723 0.88 BTN3A1 (0.52) BTN3A1ELANE
SCHEMBL23391280 0.88 MEN1 (0.40) BTN3A1KMT2AELANE
SCHEMBL15055604 0.88 MEN1 (0.40) BTN3A1KMT2AELANE
SCHEMBL16566342 0.87 BTN3A1 (0.54) BTN3A1MAPK1L3MBTL1KMT2AELANE
SCHEMBL23408491 0.85 ALDH1A1 (0.42) BTN3A1MAPK1MAPTKMT2ARECQL
SCHEMBL25387275 0.85 BTN3A1 (0.53) BTN3A1MAPK1MAPTL3MBTL1KMT2A
SCHEMBL23992574 0.85 BTN3A1 (0.53) BTN3A1MAPK1MAPTL3MBTL1KMT2A
SCHEMBL800889 0.85 BTN3A1 (0.53) BTN3A1MAPK1MAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4107164-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-12264173-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2025-04-01 US disclosed
US-20240174704-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2024-05-30 US disclosed
EP-3831388-B1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FOR USE IN SUPPRESSING ADENOVIRUS FUJIFILM CORP (JP) 2024-02-28 EP disclosed
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 US disclosed
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 US disclosed
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 US disclosed
US-20230295201-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2023-09-21 US disclosed
US-20230295201-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2023-09-21 US disclosed
EP-4106877-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-28 EP disclosed
EP-4107164-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-28 EP disclosed
US-20220356196-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2022-11-10 US disclosed
US-20210284670-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 US disclosed
US-8871737-B2 Substituted nucleotide analogs ALIOS BIOPHARMA, INC. (US) 2014-10-28 US disclosed
US-20120071434-A1 SUBSTITUTED NUCLEOTIDE ANALOGS ALIOS BIOPHARMA, INC. (US) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295201-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-20220356196-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-20210284670-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-12264173-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-11767337-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-20240174704-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885MAPK1 3406/4885MAPT 2729/4885
US-20120071434-A1 SUBSTITUTED NUCLEOTIDE ANALOGS PNP, NUDT1, TYMP BTN3A1 3215/4885MAPK1 3670/4885MAPT 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.