Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271180 | 0.83 | ENPP3 (0.31) | — | |
| SCHEMBL8874568 | 0.78 | MAPT (0.45) | CA2CA1CA4CA5ACA14 | |
| SCHEMBL9315649 | 0.74 | RAB9A (0.45) | TSHRKDM4E | |
| SCHEMBL12327638 | 0.74 | METAP2 (0.39) | — | |
| SCHEMBL27633012 | 0.72 | RAB9A (0.47) | TSHRKDM4E | |
| SCHEMBL9902185 | 0.71 | MAPT (0.43) | KDM4E | |
| SCHEMBL12263306 | 0.69 | NOTUM (0.44) | KDM4E | |
| SCHEMBL4723625 | 0.69 | ENPP3 (0.50) | CA2CA1CA7CA14KDM4E | |
| SCHEMBL13667445 | 0.68 | CA2 (0.78) | CA2CA1MGLLENPP2LPL | |
| SCHEMBL18394607 | 0.68 | CA2 (0.78) | CA2CA1MGLLENPP2LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197967-B1 | CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION | CLARIANT GMBH (DE) | 2001-03-06 | — | — | US | claimed |
| US-6197967-B1 | CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION | CLARIANT GMBH (DE) | 2001-03-06 | — | — | US | disclosed |
| US-6197967-B1 | CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION | CLARIANT GMBH (DE) | 2001-03-06 | — | — | US | disclosed |