Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.57 |
| ▸ | MMP2 | P08253 | 11/20 | 0.57 |
| ▸ | MMP3 | P08254 | 9/20 | 0.57 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507437 | 0.91 | MMP13 (0.49) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7516820 | 0.89 | MMP13 (0.54) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7898430 | 0.87 | MMP13 (0.44) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7508943 | 0.86 | MMP2 (0.53) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7509277 | 0.82 | MMP2 (0.51) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7509067 | 0.82 | MMP2 (0.52) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502278 | 0.81 | MMP13 (0.55) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7506986 | 0.81 | MMP2 (0.60) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7516549 | 0.79 | MMP1 (0.49) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7508946 | 0.79 | ALDH1A1 (0.45) | MMP13MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |