Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555636 | 0.84 | ALDH1A1 (0.59) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL7892509 | 0.84 | GAA (0.54) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL7903564 | 0.83 | ALDH1A1 (0.51) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL7905669 | 0.82 | HTR2A (0.56) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL27787118 | 0.81 | GAA (0.60) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL5765803 | 0.81 | ALDH1A1 (0.57) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL11094410 | 0.81 | ALDH1A1 (0.56) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9344653 | 0.80 | LMNA (0.57) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL1554845 | 0.80 | ALDH1A1 (0.55) | HTR2AALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL5724425 | 0.80 | ALDH1A1 (0.59) | HTR2AALDH1A1MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |