Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794355 | 0.85 | TSHR (0.43) | POLBALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL24126312 | 0.85 | CA2 (0.41) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8166836 | 0.85 | TSHR (0.36) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8174823 | 0.85 | TSHR (0.33) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL25696408 | 0.85 | CA2 (0.37) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2000756 | 0.82 | HSD11B1 (0.46) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10700852 | 0.81 | NOS3 (0.35) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6319546 | 0.81 | TSHR (0.31) | POLBALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL16340864 | 0.80 | HSD11B1 (0.44) | HSD11B1POLBALDH1A1TDP1L3MBTL1 | |
| Lithium SCHEMBL5691154 | 0.79 | HSD11B1 (0.44) | HSD11B1POLBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579870-B1 | TRKB AGONISTS AND METHODS OF USE | UNIV EMORY (US) | 2018-02-14 | — | — | EP | claimed |
| EP-2579870-A2 | TRKB AGONISTS AND METHODS OF USE | Emory University (US) | 2013-04-17 | — | — | EP | claimed |
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2013-02-14 | — | — | US | claimed |
| WO-2011156479-A9 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2012-05-31 | — | — | WO | claimed |
| WO-2011156479-A2 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2011-12-15 | — | — | WO | claimed |
| US-5075378-A | Coating of an epoxy resin, fluorocarbon polymer fluorinated curing agent | THE STANDARD OIL COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| US-5035970-A | Encapsulated toner compositions and processes thereof | XEROX CORPORATION (US) | 1991-07-30 | — | — | US | claimed |
| CN-117043232-B | Method for producing polyimide resin powder | 三菱瓦斯化学株式会社 | 2024-10-22 | — | — | CN | disclosed |
| US-20240199810-A1 | METHOD FOR PRODUCING POLYIMIDE RESIN POWDER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2024028893-A1 | SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-02-08 | — | — | WO | disclosed |
| EP-4317254-A1 | METHOD FOR PRODUCING POLYIMIDE RESIN POWDER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20240025919-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. | 2024-01-25 | — | — | US | disclosed |
| CN-117043232-A | Method for producing polyimide resin powder | 三菱瓦斯化学株式会社 | 2023-11-10 | — | — | CN | disclosed |
| EP-1517927-A1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION | DSM IP Assets B.V. (NL) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004003030-A1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION | DSM IP ASSETS B.V. (NL) | 2004-01-08 | — | — | WO | disclosed |
| EP-0880555-B1 | METHOD OF MAKING FREE-STANDING POLYIMIDE FILM | OCCIDENTAL CHEM CO (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |
| EP-0001002-B1 | INDANAMINES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0001002-A1 | Indanamines, processes for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4128666-A | PHENYLETHANOLAMINE N-METHYL-TRANSFERASE INHIBITORS | SMITHKLINE CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | NTRK2, BDNF, NTRK1 | HSD11B1 1700/4885POLB 3440/4885ALDH1A1 1116/4885 |
| US-20240025919-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | AZI2, TET3, OXA1L | HSD11B1 782/4885POLB 1891/4885ALDH1A1 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.