Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902404 | 0.89 | CCR5 (0.49) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7901721 | 0.88 | KCNH2 (0.44) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7894622 | 0.87 | HDAC1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7901870 | 0.84 | KDM1A (0.47) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL784863 | 0.76 | SIGMAR1 (0.68) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9030647 | 0.75 | SIGMAR1 (0.67) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL11313073 | 0.74 | SIGMAR1 (0.65) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL27473621 | 0.74 | SIGMAR1 (0.65) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL13478907 | 0.73 | SIGMAR1 (0.61) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL13478882 | 0.73 | KCNH2 (0.67) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |