Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894622 | 0.90 | HDAC1 (0.50) | KDM1ASIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7904409 | 0.84 | SIGMAR1 (0.52) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7902404 | 0.83 | CCR5 (0.49) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL425436 | 0.78 | KDM1A (0.44) | KDM1ASIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL446158 | 0.78 | DRD2 (0.47) | KDM1ASIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7901721 | 0.76 | KCNH2 (0.44) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14938277 | 0.74 | KDM1A (0.49) | KDM1ASIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL14937747 | 0.70 | SLC5A7 (0.42) | KDM1ADRD2DRD4NPC1RAB9A | |
| SCHEMBL530727 | 0.67 | FAAH (0.54) | KMT2ANPC1RAB9A | |
| SCHEMBL425287 | 0.66 | HDAC1 (0.52) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |