Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896392 | 0.80 | POLB (0.33) | LMNANPC1RAB9AKDM4E | |
| SCHEMBL7896420 | 0.78 | KDM1A (0.40) | KDM1AABCB1 | |
| SCHEMBL7903987 | 0.78 | KDM1A (0.40) | KDM1ALMNARAB9AABCB1 | |
| SCHEMBL7904723 | 0.75 | RAB9A (0.46) | KDM1AALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7904695 | 0.74 | F2 (0.42) | KDM1ALMNARAB9AKDM4EMAPT | |
| SCHEMBL7902694 | 0.61 | MAPK1 (0.34) | ALDH1A1HPGDKDM4EMAPTMEN1 | |
| SCHEMBL11801607 | 0.60 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDALPLKDM4E | |
| SCHEMBL29259761 | 0.59 | ALDH1A1 (0.48) | KDM1AALDH1A1LMNAHPGDALPL | |
| SCHEMBL15564280 | 0.59 | ALDH1A1 (0.48) | ALDH1A1LMNAHPGDALPLNPC1 | |
| SCHEMBL9254390 | 0.59 | POLB (0.34) | LMNANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |