Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902709 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EHRH3BACE1HDAC1 | |
| SCHEMBL7905860 | 0.87 | RAB9A (0.35) | RAB9ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL7908470 | 0.87 | HRH3 (0.44) | RAB9ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL7896445 | 0.85 | KDM4E (0.34) | RAB9ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL7896508 | 0.83 | HRH3 (0.41) | KDM4EMAPTHRH3BACE1TP53 | |
| SCHEMBL7903943 | 0.81 | QPCT (0.42) | SMN1; SMN2KDM4ELMNAMAPTHRH3 | |
| SCHEMBL7905780 | 0.79 | HRH3 (0.40) | KDM4ELMNAMAPTHRH3BACE1 | |
| SCHEMBL7896504 | 0.78 | HRH3 (0.39) | KDM4ELMNAHRH3BACE1TP53 | |
| SCHEMBL7904632 | 0.75 | HRH3 (0.41) | RAB9ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL7896418 | 0.74 | RAB9A (0.46) | RAB9ASMN1; SMN2KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |